«Sildenafil» is a drug for the treatment of erectile dysfunction in adult men. It is available in the form of film-coated tablets.

Action: When sexually aroused, sildenafil dilates the blood vessels of the penis, increasing blood flow to the tissues and improving erection. The drug only works when there is sexual stimulation.

Indications

Sildenafil is used to treat erectile dysfunction, where a man is unable to achieve or maintain an erection strong enough for sexual intercourse.

Contraindications

Do not take Sildenafil if you have:

• An allergy to sildenafil or other components of the drug.
• Concurrent use of nitric oxide donors, such as amyl nitrite, or nitrates, as this may increase their antihypertensive effect.
• Severe cardiovascular diseases in which sexual activity is not recommended.
• Concurrent use with ritonavir.

The drug is not intended for women and children under 18 years of age.

Method of administration and doses

The recommended dose for most adults is 50 mg one hour before sexual intercourse. Depending on the effectiveness and tolerability, the dose can be increased to 100 mg or decreased to 25 mg. The maximum dose is 100 mg and should be taken no more than once a day.

Features of administration:

• Taking the drug with food may delay the onset of action.
• There is no need to adjust the dose in case of mild and moderate renal impairment (creatinine clearance 30-80 ml/min). In case of severe renal impairment (CC < 30 ml/min), start with a dose of 25 mg.
• In case of liver dysfunction (e.g. cirrhosis), the dose should also be reduced to 25 mg.

Before starting treatment, be sure to consult your doctor.

Side effects

Possible side effects:

• Headache, dizziness, hot flashes, insomnia.
• Dyspepsia, diarrhea, nausea, abdominal pain.
• Arthralgia, myalgia, increased muscle tension.
• Nasal congestion, pharyngitis, sinusitis, rhinitis, respiratory tract infections, and breathing difficulties.
• Visual changes: altered color perception, increased sensitivity to light, and blurred vision. Conjunctivitis.