Azimicin is a broad-spectrum antibiotic containing azithromycin. It belongs to the macrolide-azalide group. It is used to treat infectious diseases caused by sensitive microorganisms.

Indications for use

• Infections of the respiratory tract and ENT organs: tonsillitis, sinusitis, pharyngitis, and otitis media.
• Lower respiratory tract infections: acute bronchitis, exacerbation of chronic bronchitis, pneumonia (including atypical pneumonia).
• Skin and soft tissue infections: moderate acne, erysipelas, impetigo, dermatoses.
• Uncomplicated genitourinary tract infections (chlamydia).
• Early stage of Lyme disease (migratory erythema).

Contraindications

• Allergy to azithromycin, erythromycin, macrolides, or ketolides.
• Allergy to the drug's excipients.
• Severe liver failure.
• Severe renal impairment (CrCl < 40 ml/min).
• Concurrent use with ergotamine and dihydroergotamine.
• Age under 18 years (for intravenous administration).

Administration and dosage

The drug is taken orally 1 hour before a meal or 2 hours after a meal. The dosage depends on the disease and age.

For adults:

• Respiratory and skin infections: 0.5 g once a day for 3 days (1.5 g total).
• Skin and soft tissue infections: 1 g on the first day, then 0.5 g for 5 days (3 g total).
• Urethritis or cervicitis: 1 g once.
• Lyme disease: 1 g on the first day, 0.5 g for 5 days (3 g total).
• Gastric ulcer: 1 g for 3 days as part of combination therapy.

For children over 12 years of age:

• General infections: 10 mg/kg per day for 3 days or 10 mg/kg on the first day, then 5-10 mg/kg for 4 days (30 mg/kg total).
• Lyme disease: 20 mg/kg on the first day, then 10 mg/kg for 5 days.

Side effects

Adverse reactions are possible:

• Digestive system: nausea, diarrhea, abdominal pain, vomiting, flatulence, increased liver enzymes. In children, constipation, lack of appetite, gastritis.
• Cardiovascular system: palpitations, chest pain (very rare).
• Nervous system: dizziness, headache, drowsiness, anxiety, insomnia (rarely).
• Genitourinary system: vaginal candidiasis, nephritis (less than 1%).
• Allergic reactions: rash, itching, Quincke's edema (rarely).